Optical Resolution of Racemic Jasmonic Acid by Separation of Diastereomeric Mandelyl Esters
نویسندگان
چکیده
T he reaction of racemic jasm onic acid with e ither (/?)-m andelic acid or its (S )-enan tiom er resu lted in a m ixture of d iastereom eric esters. Both the 0 -[(± )-jasm onoyI]-(/?)-m andelic acids (2a, 2b) and the 0 -[(± )-jasm onoy l]-(5 )-m andelic acids (3a, 3b) could be sep ara ted by silica gel chrom atography . By hydrolysis o f the pure d iastereom ers, resolved ( + )-JA (la) and ( — )-JA (lb) w ere o b ta ined . The structures and the purity of all com pounds w ere confirm ed by 'H N M R . MS, G C /M S, IR and O R D .
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